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Se evaluó la elegibilidad y se obtuvo el consentimiento. El oncólogo tratante completó un cuestionario, antes de obtener una biopsia de una lesión metastásica, para determinar su plan de tratamiento y la fecha de inicio propuesta. Una vez que estuvieron disponibles los resultados de la biopsia, se encuestó nuevamente a los oncólogos para determinar si su plan de tratamiento había cambiado según los resultados de la biopsia y para determinar la fecha real de inicio del tratamiento. La tasa de éxito del procedimiento se evaluó como el número de exámenes histopatológicos coincidentes de primaria y metástasis como proporción de las biopsias realizadas. El retraso de la terapia se evaluó como la duración entre las fechas de inicio del tratamiento propuestas y reales. La satisfacción del paciente se evaluó mediante cuestionarios, que se administraron a todas las mujeres que dieron su consentimiento en el momento del seguimiento clínico; estos evaluaron los efectos adversos resultantes del procedimiento de biopsia y la voluntad de recomendar la biopsia metastásica a otras mujeres
Eligibility was assessed and consent obtained. The treating oncologist completed a questionnaire, before obtaining a biopsy from a metastatic lesion, to determine their treatment plan and the proposed start date. Once biopsy results were available, oncologists were again surveyed to determine whether their treatment plan had changed based on the biopsy results and to determine the actual start date of treatment. Procedural success rate was assessed as the number of matched histopathologic examinations of primary and metastasis as a proportion of biopsies undertaken. Delay of therapy was evaluated as the duration between the proposed and actual treatment start dates. Patient satisfaction was assessed using questionnaires, which were administered to all consenting women at the time of clinic follow-up; these evaluated adverse effects resulting from the biopsy procedure and willingness to recommend metastatic biopsy to other women
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